Minimally invasive procedures are becoming the standard of care in medical surgical procedures with a proven efficacy, reduced morbidity, and recovery time. Regenerative dentistry is still based mostly on extensive surgeries with autogenous grafts as well as animal and human processed tissues. These limit the surgeon's ability to use minimally invasive approach and to achieve better long-term outcomes. The Glymatrix® technology is based on using a highly purified molecular collagen cross-linked by natural sugar, which has shown promise in production of safe and effective biomaterials that act as ossifying scaffolds and long-term membranes. These proactively promote and regenerate soft and hard tissues and allow surgeons to use minimally invasive procedures that are easier and more predictable even in the hands of less experienced clinicians. In addition, these support remnant-free, natural bone, and soft tissue that may help to reduce the incidence of peri-implantitis around osseo-integrated implants. Glymatrix technology and currently available Glymatrix-based devices will be presented together with minimally invasive GBR procedures, supported by published research, as well as clinical and histological evidence.
Define the objectives and goals of maxillofacial, minimally invasive regenerative procedures
Recognize the unique features of collagen as a basis for tissue regeneration
Identify active deviced and tissue factors that may support simple and more predictable ways to achieve true tissue regeneration