The application of growth factors has been introduced into implant dentistry mostly to enhance peri-implant bone regeneration and facilitate augmentation procedures. Among the many different factors, molecules from the bone morphogenic protein (BMP) family have proven to provide the strongest osteogenic activity. Successful application of BMPs has been shown to be linked to the use of suitable carriers that allow for the reduction of growth factor dosage through controlled delivery and thereby can achieve more effective enhancement of bone regeneration. Adverse effects such as swelling and infection have been described to occur and appear to be associated to the dosage applied. Although BMPs are already in widespread use, improvements in the application will be required to achieve controlled delivery with predictable results. This presentation reviews the positive and adverse effects of the use of osteogenic growth factors and discusses different approaches for their application.
Learning Objectives:
Learn how BMPs can affect bone regeneration and facilitate augmentation procedures
Understand how and why carrier systems can improve the efficacy of BMPs
Learn about the adverse effects of BMPs and how they can be handled
